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Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference?
There is mounting evidence that only a small fraction of early-onset Alzheimer disease cases (onset <65 years) are explained by known mutations. Even multiplex families with early onset often also have late-onset cases, suggesting that the commonly applied categorization of Alzheimer disease into...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673282/ https://www.ncbi.nlm.nih.gov/pubmed/33225065 http://dx.doi.org/10.1212/NXG.0000000000000512 |