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Late-onset vs nonmendelian early-onset Alzheimer disease: A distinction without a difference?

There is mounting evidence that only a small fraction of early-onset Alzheimer disease cases (onset <65 years) are explained by known mutations. Even multiplex families with early onset often also have late-onset cases, suggesting that the commonly applied categorization of Alzheimer disease into...

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Detalles Bibliográficos
Autores principales: Reitz, Christiane, Rogaeva, Ekaterina, Beecham, Gary W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673282/
https://www.ncbi.nlm.nih.gov/pubmed/33225065
http://dx.doi.org/10.1212/NXG.0000000000000512