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Berberine alleviates palmitic acid-induced podocyte apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress

Lipid accumulation in podocytes can lead to the destruction of cellular morphology, in addition to cell dysfunction and apoptosis, which is a key factor in the progression of chronic kidney disease (CKD). Berberine (BBR) is an isoquinoline alkaloid extracted from medicinal plants such as Coptis chin...

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Detalles Bibliográficos
Autores principales: Xiang, Xing-Yang, Liu, Ting, Wu, Yue, Jiang, Xu-Shun, He, Jun-Ling, Chen, Xue-Mei, Du, Xiao-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673344/
https://www.ncbi.nlm.nih.gov/pubmed/33179098
http://dx.doi.org/10.3892/mmr.2020.11641