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Efficient and crucial quality control of HAP1 cell ploidy status

The near-haploid human cell line HAP1 recently became a popular subject for CRISPR/Cas9 editing, since only one allele requires modification. Through the gene-editing service at Horizon Discovery, there are at present more than 7500 edited cell lines available and the number continuously increases....

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Detalles Bibliográficos
Autores principales: Beigl, Tobias B., Kjosås, Ine, Seljeseth, Emilie, Glomnes, Nina, Aksnes, Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673356/
https://www.ncbi.nlm.nih.gov/pubmed/33184093
http://dx.doi.org/10.1242/bio.057174