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Does Cholinergic Stimulation Affect the P2X7 Receptor-Mediated Dye Uptake in Mast Cells and Macrophages?

Background: Extracellular ATP is a powerful trigger of neuroinflammation by activating immune cells via P2X7 receptors. Acetylcholine and nicotinic agonists inhibit ATP-triggered proinflammatory cytokines via the so-called “cholinergic anti-inflammatory pathway” (CAP). However, it remains unclear as...

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Detalles Bibliográficos
Autores principales: Nurkhametova, Dilyara, Siniavin, Andrei, Streltsova, Maria, Kudryavtsev, Denis, Kudryavtsev, Igor, Giniatullina, Raisa, Tsetlin, Victor, Malm, Tarja, Giniatullin, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673375/
https://www.ncbi.nlm.nih.gov/pubmed/33328886
http://dx.doi.org/10.3389/fncel.2020.548376