The Antidepressant Mirtazapine Activates Hepatic Macrophages, Facilitating Pathogen Clearance While Limiting Tissue Damage in Mice

BACKGROUND AND AIMS: Mirtazapine is an atypical antidepressant with antagonist activity for serotonin and histamine receptors. Clinical and experimental evidence suggests that, in addition to treating depression, mirtazapine also alters liver innate immunity and suppresses immune-driven hepatic macr...

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Detalles Bibliográficos
Autores principales: Davis, Rachelle Paige, Almishri, Wagdi, Jenne, Craig Neal, Swain, Mark Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673391/
https://www.ncbi.nlm.nih.gov/pubmed/33250892
http://dx.doi.org/10.3389/fimmu.2020.578654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673391/
https://www.ncbi.nlm.nih.gov/pubmed/33250892
http://dx.doi.org/10.3389/fimmu.2020.578654

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