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The Expression Pattern and Clinical Significance of the Immune Checkpoint Regulator VISTA in Human Breast Cancer

BACKGROUND: Immunotherapies targeting CTLA-4 and PD-1 have elicited promising responses in a variety of cancers. However, the relatively low response rates warrant the identification of additional immunosuppressive pathways. V domain immunoglobulin suppressor of T cell activation (VISTA) plays a cri...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoxue, Zhang, Junying, Shi, Zhongyuan, Liu, Wanmei, Hu, Xinlei, Qie, Chenxin, Chen, Wenting, Wang, Yan, Wang, Li, Jiang, Jingwei, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673447/
https://www.ncbi.nlm.nih.gov/pubmed/33250890
http://dx.doi.org/10.3389/fimmu.2020.563044