TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness

PURPOSE: This study aimed to investigate the effects of substratum stiffness on the sensitivity of human conjunctival fibroblasts to transforming growth factor (TGF)-β, and to explore the molecular mechanism of action. METHODS: Human conjunctival fibroblasts were cultured on collagen-coated plastic...

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Detalles Bibliográficos
Autores principales: Matsumura, Tomoyo, Fujimoto, Tomokazu, Futakuchi, Akiko, Takihara, Yuji, Watanabe-Kitamura, Fumika, Takahashi, Eri, Inoue-Mochita, Miyuki, Tanihara, Hidenobu, Inoue, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673499/
https://www.ncbi.nlm.nih.gov/pubmed/33206726
http://dx.doi.org/10.1371/journal.pone.0242626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673499/
https://www.ncbi.nlm.nih.gov/pubmed/33206726
http://dx.doi.org/10.1371/journal.pone.0242626

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