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TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
PURPOSE: This study aimed to investigate the effects of substratum stiffness on the sensitivity of human conjunctival fibroblasts to transforming growth factor (TGF)-β, and to explore the molecular mechanism of action. METHODS: Human conjunctival fibroblasts were cultured on collagen-coated plastic...
Autores principales: | Matsumura, Tomoyo, Fujimoto, Tomokazu, Futakuchi, Akiko, Takihara, Yuji, Watanabe-Kitamura, Fumika, Takahashi, Eri, Inoue-Mochita, Miyuki, Tanihara, Hidenobu, Inoue, Toshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673499/ https://www.ncbi.nlm.nih.gov/pubmed/33206726 http://dx.doi.org/10.1371/journal.pone.0242626 |
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