Biophysical and X-ray structural studies of the (GGGTT)(3)GGG G-quadruplex in complex with N-methyl mesoporphyrin IX

The G-quadruplex (GQ) is a well-studied non-canonical DNA structure formed by G-rich sequences found at telomeres and gene promoters. Biological studies suggest that GQs may play roles in regulating gene expression, DNA replication, and DNA repair. Small molecule ligands were shown to alter GQ struc...

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Detalles Bibliográficos
Autores principales: Lin, Linda Yingqi, McCarthy, Sawyer, Powell, Barrett M., Manurung, Yanti, Xiang, Irene M., Dean, William L., Chaires, Brad, Yatsunyk, Liliya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673559/
https://www.ncbi.nlm.nih.gov/pubmed/33206666
http://dx.doi.org/10.1371/journal.pone.0241513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673559/
https://www.ncbi.nlm.nih.gov/pubmed/33206666
http://dx.doi.org/10.1371/journal.pone.0241513

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