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Biophysical and X-ray structural studies of the (GGGTT)(3)GGG G-quadruplex in complex with N-methyl mesoporphyrin IX
The G-quadruplex (GQ) is a well-studied non-canonical DNA structure formed by G-rich sequences found at telomeres and gene promoters. Biological studies suggest that GQs may play roles in regulating gene expression, DNA replication, and DNA repair. Small molecule ligands were shown to alter GQ struc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673559/ https://www.ncbi.nlm.nih.gov/pubmed/33206666 http://dx.doi.org/10.1371/journal.pone.0241513 |