Cargando…
TRPML2 is an osmo/mechanosensitive cation channel in endolysosomal organelles
Endolysosomes are dynamic, intracellular compartments, regulating their surface-to-volume ratios to counteract membrane swelling or shrinkage caused by osmotic challenges upon tubulation and vesiculation events. While osmosensitivity has been extensively described on the plasma membrane, the mechani...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673730/ https://www.ncbi.nlm.nih.gov/pubmed/33177082 http://dx.doi.org/10.1126/sciadv.abb5064 |