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DORGE: Discovery of Oncogenes and tumoR suppressor genes using Genetic and Epigenetic features

Data-driven discovery of cancer driver genes, including tumor suppressor genes (TSGs) and oncogenes (OGs), is imperative for cancer prevention, diagnosis, and treatment. Although epigenetic alterations are important for tumor initiation and progression, most known driver genes were identified based...

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Detalles Bibliográficos
Autores principales: Lyu, Jie, Li, Jingyi Jessica, Su, Jianzhong, Peng, Fanglue, Chen, Yiling Elaine, Ge, Xinzhou, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673741/
https://www.ncbi.nlm.nih.gov/pubmed/33177077
http://dx.doi.org/10.1126/sciadv.aba6784