Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons

Genetic mutations in the gene encoding transport protein particle complex 9 (trappc9), a subunit of TRAPP that acts as a guanine nucleotide exchange factor for rab proteins, cause intellectual disability with brain structural malformations by elusive mechanisms. Here, we report that trappc9-deficien...

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Detalles Bibliográficos
Autores principales: Ke, Yuting, Weng, Meiqian, Chhetri, Gaurav, Usman, Muhammad, Li, Yan, Yu, Qing, Ding, Yingzhuo, Wang, Zejian, Wang, Xiaolong, Sultana, Pinky, DiFiglia, Marian, Li, Xueyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673810/
https://www.ncbi.nlm.nih.gov/pubmed/33208359
http://dx.doi.org/10.1126/sciadv.abb7781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673810/
https://www.ncbi.nlm.nih.gov/pubmed/33208359
http://dx.doi.org/10.1126/sciadv.abb7781

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