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Aberrant ALOX5 Activation Correlates with HER2 Status and Mediates Breast Cancer Biological Activities through Multiple Mechanisms

Arachidonate lipoxygenases (ALOX) have been implicated in playing a critical role in tumorigenesis, development, and metastasis. We previously reported that ALOX12 is involved in breast cancer chemoresistance. In this study, we demonstrate that the ALOX5 activation correlates with the HER2 expressio...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao, Jiang, Yi, Li, Qiuyun, Huang, Zhen, Yang, Huawei, Wei, Changyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673939/
https://www.ncbi.nlm.nih.gov/pubmed/33224971
http://dx.doi.org/10.1155/2020/1703531