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Reactive oxygen species-induced activation of Yes-associated protein-1 through the c-Myc pathway is a therapeutic target in hepatocellular carcinoma

BACKGROUND: The Hippo signaling pathway regulates organ size by regulating cell proliferation and apoptosis with terminal effectors including Yes-associated protein-1 (YAP-1). Dysregulation in Hippo pathway has been proposed as one of the therapeutic targets in hepatocarcinogenesis. The levels of re...

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Detalles Bibliográficos
Autores principales: Cho, Yuri, Park, Min Ji, Kim, Koeun, Kim, Sun Woong, Kim, Wonjin, Oh, Sooyeon, Lee, Joo Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673967/
https://www.ncbi.nlm.nih.gov/pubmed/33268949
http://dx.doi.org/10.3748/wjg.v26.i42.6599