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Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses

SARS-CoV-2 infection is characterized by peak viral load in the upper airway prior to or at the time of symptom onset, an unusual feature that has enabled widespread transmission of the virus and precipitated a global pandemic. How SARS-CoV-2 is able to achieve high titer in the absence of symptoms...

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Detalles Bibliográficos
Autores principales: Mick, Eran, Kamm, Jack, Pisco, Angela Oliveira, Ratnasiri, Kalani, Babik, Jennifer M., Castañeda, Gloria, DeRisi, Joseph L., Detweiler, Angela M., Hao, Samantha L., Kangelaris, Kirsten N., Kumar, G. Renuka, Li, Lucy M., Mann, Sabrina A., Neff, Norma, Prasad, Priya A., Serpa, Paula Hayakawa, Shah, Sachin J., Spottiswoode, Natasha, Tan, Michelle, Calfee, Carolyn S., Christenson, Stephanie A., Kistler, Amy, Langelier, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673985/
https://www.ncbi.nlm.nih.gov/pubmed/33203890
http://dx.doi.org/10.1038/s41467-020-19587-y