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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

Human transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative pathogen of the COVID-19 pandemic, exerts a massive health and socioeconomic crisis. The virus infects alveolar epithelial type 2 cells (AT2s), leading to lung injury and impaired gas exchange, but the mech...

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Detalles Bibliográficos
Autores principales: Hekman, Ryan M., Hume, Adam J., Goel, Raghuveera Kumar, Abo, Kristine M., Huang, Jessie, Blum, Benjamin C., Werder, Rhiannon B., Suder, Ellen L., Paul, Indranil, Phanse, Sadhna, Youssef, Ahmed, Alysandratos, Konstantinos D., Padhorny, Dzmitry, Ojha, Sandeep, Mora-Martin, Alexandra, Kretov, Dmitry, Ash, Peter E.A., Verma, Mamta, Zhao, Jian, Patten, J.J., Villacorta-Martin, Carlos, Bolzan, Dante, Perea-Resa, Carlos, Bullitt, Esther, Hinds, Anne, Tilston-Lunel, Andrew, Varelas, Xaralabos, Farhangmehr, Shaghayegh, Braunschweig, Ulrich, Kwan, Julian H., McComb, Mark, Basu, Avik, Saeed, Mohsan, Perissi, Valentina, Burks, Eric J., Layne, Matthew D., Connor, John H., Davey, Robert, Cheng, Ji-Xin, Wolozin, Benjamin L., Blencowe, Benjamin J., Wuchty, Stefan, Lyons, Shawn M., Kozakov, Dima, Cifuentes, Daniel, Blower, Michael, Kotton, Darrell N., Wilson, Andrew A., Mühlberger, Elke, Emili, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
https://www.ncbi.nlm.nih.gov/pubmed/33259812
http://dx.doi.org/10.1016/j.molcel.2020.11.028