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CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2
Our previous work demonstrated that Piwil2 reactivated by the human papillomavirus oncoproteins E6 and E7 may reprogram somatic cells into tumor-initiating cells (TICs), which contribute to cervical neoplasia lesions. Maintaining the stemness of TICs is critical for the progression of cervical lesio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674161/ https://www.ncbi.nlm.nih.gov/pubmed/33190089 http://dx.doi.org/10.1016/j.neo.2020.10.013 |