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Targeted Mass Spectrometry of a Clinically Relevant PSA Variant from Post‐DRE Urines for Quantitation and Genotype Determination

PURPOSE: The rs17632542 single nucleotide polymorphism (SNP) results in lower serum prostate specific antigen (PSA) levels which may further mitigate against its clinical utility as a prostate cancer biomarker. Post‐digital rectal exam (post‐DRE) urine is a minimally invasive fluid that is currently...

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Detalles Bibliográficos
Autores principales: Otto, Joseph J., Correll, Vanessa L., Engstroem, Hampus A., Hitefield, Naomi L., Main, Brian P., Albracht, Brenna, Johnson‐Pais, Teresa, Yang, Li Fang, Liss, Michael, Boutros, Paul C., Kislinger, Thomas, Leach, Robin J., Semmes, Oliver J., Nyalwidhe, Julius O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674190/
https://www.ncbi.nlm.nih.gov/pubmed/32614141
http://dx.doi.org/10.1002/prca.202000012