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Virtual Screening for Novel SarA Inhibitors to Prevent Biofilm Formation of Staphylococcus aureus in Prosthetic Joint Infections

Staphylococcus aureus is one of the predominant causes of periprosthetic joint infections (PJIs). Bacterial adhesion and biofilm formation are important factors in the pathogenesis of PJIs. S. aureus biofilm formation is regulated by several factors, including S. aureus regulator A (SarA). Previous...

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Detalles Bibliográficos
Autores principales: Yu, Jinlong, Jiang, Feng, Zhang, Feiyang, Pan, Yunqi, Wang, Jianqiang, Han, Pei, Tang, Jin, Shen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674313/
https://www.ncbi.nlm.nih.gov/pubmed/33224124
http://dx.doi.org/10.3389/fmicb.2020.587175