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Mechanisms of ranolazine pretreatment in preventing ventricular tachyarrhythmias in diabetic db/db mice with acute regional ischemia–reperfusion injury

Studies have demonstrated that diabetic (db/db) mice have increased susceptibility to myocardial ischemia–reperfusion (IR) injury and ventricular tachyarrhythmias (VA). We aimed to investigate the antiarrhythmic and molecular mechanisms of ranolazine in db/db mouse hearts with acute IR injury. Ranol...

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Detalles Bibliográficos
Autores principales: Chou, Chung-Chuan, Lee, Hui-Ling, Chang, Gwo-Jyh, Wo, Hung-Ta, Yen, Tzung-Hai, Wen, Ming-Shien, Chu, Yen, Liu, Hao-Tien, Chang, Po-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674419/
https://www.ncbi.nlm.nih.gov/pubmed/33208777
http://dx.doi.org/10.1038/s41598-020-77014-0