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Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects

COPD, chronic bronchitis (CB) and active smoking have all been associated with goblet cell hyperplasia (GCH) in small studies. Active smoking is strongly associated with CB, but there is a disconnect between CB clinical symptoms and pathology. Chronic cough and sputum production poorly correlate wit...

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Detalles Bibliográficos
Autores principales: Kim, Victor, Jeong, Stephanie, Zhao, Huaqing, Kesimer, Mehmet, Boucher, Richard C., Wells, J. Michael, Christenson, Stephanie A., Han, MeiLan K., Dransfield, Mark, Paine, Robert, Cooper, Christopher B., Barjaktarevic, Igor, Bowler, Russell, Curtis, Jeffrey L., Kaner, Robert J., O’Beirne, Sarah L., O’Neal, Wanda K., Rennard, Stephen I., Martinez, Fernando J., Woodruff, Prescott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674445/
https://www.ncbi.nlm.nih.gov/pubmed/33208859
http://dx.doi.org/10.1038/s41598-020-77229-1