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Benefits and constrains of covalency: the role of loop length in protein stability and ligand binding
Protein folding is governed by non-covalent interactions under the benefits and constraints of the covalent linkage of the backbone chain. In the current work we investigate the influence of loop length variation on the free energies of folding and ligand binding in a small globular single-domain pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674454/ https://www.ncbi.nlm.nih.gov/pubmed/33208843 http://dx.doi.org/10.1038/s41598-020-76598-x |