Modulation of Cancer-Associated Fibrotic Stroma by An Integrin α(v)β(3) Targeting Protein for Pancreatic Cancer Treatment

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is resistant to most therapeutics owing to dense fibrotic stroma orchestrated by cancer-associated pancreatic stellate cells (CAPaSC). CAPaSC also support cancer cell growth, metastasis, and resistance to apoptosis. Currently, there is n...

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Detalles Bibliográficos
Autores principales: Turaga, Ravi Chakra, Sharma, Malvika, Mishra, Falguni, Krasinskas, Alyssa, Yuan, Yi, Yang, Jenny J., Wang, Shiyuan, Liu, Chunfeng, Li, Sun, Liu, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674520/
https://www.ncbi.nlm.nih.gov/pubmed/32810598
http://dx.doi.org/10.1016/j.jcmgh.2020.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674520/
https://www.ncbi.nlm.nih.gov/pubmed/32810598
http://dx.doi.org/10.1016/j.jcmgh.2020.08.004

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