Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan

BACKGROUND: Lethal B. anthracis infection produces high proinflammatory peptidoglycan (PGN) burdens in hosts. We investigated whether the lethality and inflammation anthrax PGN can produce are related. METHODS: At 6 h before and the start of 24 h anthrax PGN infusions, rats (n = 198) were treated wi...

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Detalles Bibliográficos
Autores principales: Li, Yan, Cui, Xizhong, Shiloach, Joseph, Wang, Jeffrey, Suffredini, Dante A., Xu, Wanying, Liu, Wancang, Fitz, Yvonne, Sun, Junfeng, Eichacker, Peter Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674536/
https://www.ncbi.nlm.nih.gov/pubmed/33206255
http://dx.doi.org/10.1186/s40635-020-00358-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674536/
https://www.ncbi.nlm.nih.gov/pubmed/33206255
http://dx.doi.org/10.1186/s40635-020-00358-4

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