HPS1 Regulates the Maturation of Large Dense Core Vesicles and Lysozyme Secretion in Paneth Cells

HPS1, a BLOC-3 subunit that acts as a guanine nucleotide exchange factor of Rab32/38, may play a role in the removal of VAMP7 during the maturation of large dense core vesicles of Paneth cells. Loss of HPS1 impairs lysozyme secretion and alters the composition of intestinal microbiota, which may exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jiaying, He, Xin, Wei, Aihua, Liu, Teng, Zhang, Qin, Pan, Ying, Hao, Zhenhua, Yang, Lin, Yuan, Yefeng, Zhang, Zhao, Zhang, Chang, Hao, Chanjuan, Liu, Zhihua, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674556/
https://www.ncbi.nlm.nih.gov/pubmed/33224134
http://dx.doi.org/10.3389/fimmu.2020.560110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674556/
https://www.ncbi.nlm.nih.gov/pubmed/33224134
http://dx.doi.org/10.3389/fimmu.2020.560110

Ejemplares similares