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Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

Excessive ethanol exposure can cause mitochondrial and cellular toxicity. In order to discover potential counteracting interventions, it is essential to develop assays capable of capturing the consequences of ethanol exposure in human neurons, and particularly dopaminergic neurons that are crucial f...

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Detalles Bibliográficos
Autores principales: Zink, Annika, Conrad, Josefin, Telugu, Narasimha Swami, Diecke, Sebastian, Heinz, Andreas, Wanker, Erich, Priller, Josef, Prigione, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674658/
https://www.ncbi.nlm.nih.gov/pubmed/33224955
http://dx.doi.org/10.3389/fcell.2020.590540