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Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay
Excessive ethanol exposure can cause mitochondrial and cellular toxicity. In order to discover potential counteracting interventions, it is essential to develop assays capable of capturing the consequences of ethanol exposure in human neurons, and particularly dopaminergic neurons that are crucial f...
Autores principales: | Zink, Annika, Conrad, Josefin, Telugu, Narasimha Swami, Diecke, Sebastian, Heinz, Andreas, Wanker, Erich, Priller, Josef, Prigione, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674658/ https://www.ncbi.nlm.nih.gov/pubmed/33224955 http://dx.doi.org/10.3389/fcell.2020.590540 |
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