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Is Crocin a Potential Anti-tumor Candidate Targeting Microtubules? Computational Insights From Molecular Docking and Dynamics Simulations

Although it is known crocin, a hydrophilic compound from the herbal plant Crocus sativus L., has promising antitumor activity, the detailed mechanism of its antitumor activity was not well understood. Recent experiments suggested tubulin as the primary target for the antitumor activity of crocin. Ho...

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Detalles Bibliográficos
Autores principales: Wang, Ze, Ren, Juan, Jin, Nengzhi, Liu, Xingyi, Li, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674667/
https://www.ncbi.nlm.nih.gov/pubmed/33251248
http://dx.doi.org/10.3389/fmolb.2020.586970