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Sterility of gamma-irradiated pathogens: a new mathematical formula to calculate sterilizing doses

In recent years there has been increasing advocacy for highly immunogenic gamma-irradiated vaccines, several of which are currently in clinical or pre-clinical trials. Importantly, various methods of mathematical modelling and sterility testing are employed to ensure sterility. However, these method...

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Detalles Bibliográficos
Autores principales: Singleton, Eve V, David, Shannon C, Davies, Justin B, Hirst, Timothy R, Paton, James C, Beard, Michael R, Hemmatzadeh, Farhid, Alsharifi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674690/
https://www.ncbi.nlm.nih.gov/pubmed/32930781
http://dx.doi.org/10.1093/jrr/rraa076