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Stochastic Gain and Loss of Novel Transcribed Open Reading Frames in the Human Lineage
In addition to known genes, much of the human genome is transcribed into RNA. Chance formation of novel open reading frames (ORFs) can lead to the translation of myriad new proteins. Some of these ORFs may yield advantageous adaptive de novo proteins. However, widespread translation of noncoding DNA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674706/ https://www.ncbi.nlm.nih.gov/pubmed/33210146 http://dx.doi.org/10.1093/gbe/evaa194 |