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Stochastic Gain and Loss of Novel Transcribed Open Reading Frames in the Human Lineage

In addition to known genes, much of the human genome is transcribed into RNA. Chance formation of novel open reading frames (ORFs) can lead to the translation of myriad new proteins. Some of these ORFs may yield advantageous adaptive de novo proteins. However, widespread translation of noncoding DNA...

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Detalles Bibliográficos
Autores principales:	Dowling, Daniel, Schmitz, Jonathan F, Bornberg-Bauer, Erich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674706/ https://www.ncbi.nlm.nih.gov/pubmed/33210146 http://dx.doi.org/10.1093/gbe/evaa194

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