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Identifying Differing Intracellular Cargo Release Mechanisms by Monitoring In Vitro Drug Delivery from MOFs in Real Time

Metal-organic frameworks (MOFs) have been proposed as biocompatible candidates for the targeted intracellular delivery of chemotherapeutic payloads, but the site of drug loading and subsequent effect on intracellular release is often overlooked. Here, we analyze doxorubicin delivery to cancer cells...

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Detalles Bibliográficos
Autores principales: Markopoulou, Panagiota, Panagiotou, Nikolaos, Li, Aurelia, Bueno-Perez, Rocio, Madden, David, Buchanan, Sarah, Fairen-Jimenez, David, Shiels, Paul G., Forgan, Ross S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674849/
https://www.ncbi.nlm.nih.gov/pubmed/33244524
http://dx.doi.org/10.1016/j.xcrp.2020.100254