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Identifying Differing Intracellular Cargo Release Mechanisms by Monitoring In Vitro Drug Delivery from MOFs in Real Time
Metal-organic frameworks (MOFs) have been proposed as biocompatible candidates for the targeted intracellular delivery of chemotherapeutic payloads, but the site of drug loading and subsequent effect on intracellular release is often overlooked. Here, we analyze doxorubicin delivery to cancer cells...
Autores principales: | Markopoulou, Panagiota, Panagiotou, Nikolaos, Li, Aurelia, Bueno-Perez, Rocio, Madden, David, Buchanan, Sarah, Fairen-Jimenez, David, Shiels, Paul G., Forgan, Ross S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674849/ https://www.ncbi.nlm.nih.gov/pubmed/33244524 http://dx.doi.org/10.1016/j.xcrp.2020.100254 |
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