Identification of 8-Azaguanine Biosynthesis–Related Genes Provides Insight Into the Enzymatic and Non-enzymatic Biosynthetic Pathway for 1,2,3-Triazole

8-Azaguanine (1) is a special 1,2,3-triazole containing natural product that possesses potent antibacterial and antitumor activities. In the present study, the entire 8-azaguanine biosynthetic gene cluster was located from Streptomyces CGMCC4.1633. Targeted gene disruption, heterologous expression a...

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Detalles Bibliográficos
Autores principales: Hou, Feifei, Wan, Yupeng, Gan, Qi, Xian, Mo, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674941/
https://www.ncbi.nlm.nih.gov/pubmed/33251204
http://dx.doi.org/10.3389/fbioe.2020.603514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674941/
https://www.ncbi.nlm.nih.gov/pubmed/33251204
http://dx.doi.org/10.3389/fbioe.2020.603514

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