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Intrauterine Inflammation Alters the Transcriptome and Metabolome in Placenta

Placental insufficiency is implicated in spontaneous preterm birth (SPTB) associated with intrauterine inflammation. We hypothesized that intrauterine inflammation leads to deficits in the capacity of the placenta to maintain bioenergetic and metabolic stability during pregnancy ultimately resulting...

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Detalles Bibliográficos
Autores principales: Lien, Yu-Chin, Zhang, Zhe, Barila, Guillermo, Green-Brown, Amy, Elovitz, Michal A., Simmons, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674943/
https://www.ncbi.nlm.nih.gov/pubmed/33250783
http://dx.doi.org/10.3389/fphys.2020.592689