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Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways

Adiponectin, an adipose-derived adipokine, possesses a hepatoprotective role in various liver disorders. It has been reported that hypoadiponectinemia can affect with the progression of non-alcoholic fatty liver diseases (NAFLD). Inflammasome activation has been recognized to play a major role durin...

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Detalles Bibliográficos
Autores principales: Dong, Zhixia, Zhuang, Qian, Ye, Xin, Ning, Min, Wu, Shan, Lu, Lungen, Wan, Xinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674946/
https://www.ncbi.nlm.nih.gov/pubmed/33251225
http://dx.doi.org/10.3389/fmed.2020.546445