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Traumatic Brain Injury Diminishes Feedforward Activation of Parvalbumin-Expressing Interneurons in the Dentate Gyrus

Traumatic brain injury (TBI) is associated with aberrant network hyperexcitability in the dentate gyrus (DG). GABA(A)ergic parvalbumin-expressing interneurons (PV-INs) in the DG regulate network excitability with strong, perisomatic inhibition, although the posttraumatic effects on PV-IN function af...

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Detalles Bibliográficos
Autores principales: Folweiler, Kaitlin A., Xiong, Guoxiang, Best, Kaitlin M., Metheny, Hannah E., Nah, Gabriel, Cohen, Akiva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675145/
https://www.ncbi.nlm.nih.gov/pubmed/33106385
http://dx.doi.org/10.1523/ENEURO.0195-19.2020