Enantioselective Synthesis of γ-Phenyl-γ-amino Vinyl Phosphonates and Sulfones and Their Application to the Synthesis of Novel Highly Potent Antimalarials

[Image: see text] Racemic and enantioselective syntheses of γ-phenyl-γ-amino vinyl phosphonates and sulfones have been achieved using Horner–Wadsworth–Emmons olefination of trityl protected α-phenyl-α-amino aldehydes with tetraethyl methylenediphosphonate and diethyl ((phenylsulfonyl)methyl)phosphon...

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Detalles Bibliográficos
Autores principales: Aratikatla, Eswar K., Kalamuddin, Md, Malhotra, Pawan, Mohmmed, Asif, Bhattacharya, Asish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675543/
https://www.ncbi.nlm.nih.gov/pubmed/33225134
http://dx.doi.org/10.1021/acsomega.0c03470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675543/
https://www.ncbi.nlm.nih.gov/pubmed/33225134
http://dx.doi.org/10.1021/acsomega.0c03470

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