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Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3)

BACKGROUND: Safe and effective therapies for COVID-19 are urgently needed. In order to meet this need, the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public-private partnership initiated the Therapeutics for Inpatients with COVID-19 (TICO). TICO is a multi-arm, multi-stage...

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Detalles Bibliográficos
Autores principales: Murray, Daniel D., Babiker, Abdel G., Baker, Jason V., Barkauskas, Christina E., Brown, Samuel M., Chang, Christina C., Davey, Victoria J., Gelijns, Annetine C., Ginde, Adit A., Grund, Birgit, Higgs, Elizabeth, Hudson, Fleur, Kan, Virginia L., Lane, H. Clifford, Murray, Thomas A., Paredes, Roger, Parmar, Mahesh K.B., Pett, Sarah, Phillips, Andrew N., Polizzotto, Mark N., Reilly, Cavan, Sandkovsky, Uriel, Sharma, Shweta, Teitelbaum, Marc, Thompson, B. Taylor, Young, Barnaby E., Neaton, James D., Lundgren, Jens D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675662/
https://www.ncbi.nlm.nih.gov/pubmed/33215168
http://dx.doi.org/10.1101/2020.11.08.20227876