Temporal dissociation of phencyclidine: Induced locomotor and social alterations in rats using an automated homecage monitoring system – implications for the 3Rs and preclinical drug discovery

BACKGROUND: Rodent behavioural assays are widely used to delineate the mechanisms of psychiatric disorders and predict the efficacy of drug candidates. Conventional behavioural paradigms are restricted to short time windows and involve transferring animals from the homecage to unfamiliar apparatus w...

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Detalles Bibliográficos
Autores principales: Mitchell, Emma J, Brett, Ros R, Armstrong, J Douglas, Sillito, Rowland R, Pratt, Judith A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675779/
https://www.ncbi.nlm.nih.gov/pubmed/32438848
http://dx.doi.org/10.1177/0269881120920455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675779/
https://www.ncbi.nlm.nih.gov/pubmed/32438848
http://dx.doi.org/10.1177/0269881120920455

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