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Multicellular contractility contributes to the emergence of mesothelioma nodules

Malignant pleural mesothelioma (MPM) has an overall poor prognosis and unsatisfactory treatment options. MPM nodules, protruding into the pleural cavity may have growth and spreading dynamics distinct that of other solid tumors. We demonstrate that multicellular aggregates can develop spontaneously...

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Detalles Bibliográficos
Autores principales: Tarnoki-Zach, Julia, Stockhammer, Paul, Isai, Dona Greta, Mehes, Elod, Szeder, Balint, Kovacs, Ildiko, Bugyik, Edina, Paku, Sandor, Berger, Walter, Thomas, Sufi Mary, Neufeld, Zoltan, Dome, Balazs, Hegedus, Balazs, Czirok, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675981/
https://www.ncbi.nlm.nih.gov/pubmed/33208866
http://dx.doi.org/10.1038/s41598-020-76641-x