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Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death

Podocytes are critical for the maintenance of kidney ultrafiltration barrier and play a key role in the progression of glomerular diseases. Although mediator complex proteins have been shown to be important for many physiological and pathological processes, their role in kidney tissue has not been s...

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Detalles Bibliográficos
Autores principales: Rodriguez, Patricia Q., Unnersjö-Jess, David, Zambrano, Sonia S., Guo, Jing, Möller-Hackbarth, Katja, Blom, Hans, Jahnukainen, Timo, Ebarasi, Lwaki, Patrakka, Jaakko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676236/
https://www.ncbi.nlm.nih.gov/pubmed/33208756
http://dx.doi.org/10.1038/s41598-020-76870-0