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Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death
Podocytes are critical for the maintenance of kidney ultrafiltration barrier and play a key role in the progression of glomerular diseases. Although mediator complex proteins have been shown to be important for many physiological and pathological processes, their role in kidney tissue has not been s...
Autores principales: | Rodriguez, Patricia Q., Unnersjö-Jess, David, Zambrano, Sonia S., Guo, Jing, Möller-Hackbarth, Katja, Blom, Hans, Jahnukainen, Timo, Ebarasi, Lwaki, Patrakka, Jaakko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676236/ https://www.ncbi.nlm.nih.gov/pubmed/33208756 http://dx.doi.org/10.1038/s41598-020-76870-0 |
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