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A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations

Liver metastasis is a recalcitrant disease that usually leads to death of the patient. The present study established a unique patient-derived orthotopic xenograft (PDOX) nude mouse model of a highly aggressive liver metastasis of colon cancer. The aim of the present study was to demonstrate proof-of...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiying, Hu, Kaiwen, Miyake, Kentaro, Kiyuna, Tasuku, Oshiro, Hiromichi, Wangsiricharoen, Sintawat, Kawaguchi, Kei, Higuchi, Takashi, Razmjooei, Sahar, Miyake, Masuyo, Chawla, Sant P., Singh, Shree Ram, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676248/
https://www.ncbi.nlm.nih.gov/pubmed/33208807
http://dx.doi.org/10.1038/s41598-020-76708-9