Cargando…
A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations
Liver metastasis is a recalcitrant disease that usually leads to death of the patient. The present study established a unique patient-derived orthotopic xenograft (PDOX) nude mouse model of a highly aggressive liver metastasis of colon cancer. The aim of the present study was to demonstrate proof-of...
Autores principales: | Zhang, Zhiying, Hu, Kaiwen, Miyake, Kentaro, Kiyuna, Tasuku, Oshiro, Hiromichi, Wangsiricharoen, Sintawat, Kawaguchi, Kei, Higuchi, Takashi, Razmjooei, Sahar, Miyake, Masuyo, Chawla, Sant P., Singh, Shree Ram, Hoffman, Robert M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676248/ https://www.ncbi.nlm.nih.gov/pubmed/33208807 http://dx.doi.org/10.1038/s41598-020-76708-9 |
Ejemplares similares
-
Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
por: Kiyuna, Tasuku, et al.
Publicado: (2018) -
Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy
por: Miyake, Kentaro, et al.
Publicado: (2018) -
Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2018) -
Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models
por: Murakami, Takashi, et al.
Publicado: (2019) -
Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models
por: Kawaguchi, Kei, et al.
Publicado: (2017)