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A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections

Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) from nuclear RNA bound to replicating viral sequence...

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Detalles Bibliográficos
Autores principales: Rogan, Peter K., Mucaki, Eliseos J., Shirley, Ben C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676395/
https://www.ncbi.nlm.nih.gov/pubmed/33299552
http://dx.doi.org/10.12688/f1000research.25390.2