dearseq: a variance component score test for RNA-seq differential analysis that effectively controls the false discovery rate

RNA-seq studies are growing in size and popularity. We provide evidence that the most commonly used methods for differential expression analysis (DEA) may yield too many false positive results in some situations. We present dearseq, a new method for DEA that controls the false discovery rate (FDR) w...

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Detalles Bibliográficos
Autores principales: Gauthier, Marine, Agniel, Denis, Thiébaut, Rodolphe, Hejblum, Boris P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676475/
https://www.ncbi.nlm.nih.gov/pubmed/33575637
http://dx.doi.org/10.1093/nargab/lqaa093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676475/
https://www.ncbi.nlm.nih.gov/pubmed/33575637
http://dx.doi.org/10.1093/nargab/lqaa093

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