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dearseq: a variance component score test for RNA-seq differential analysis that effectively controls the false discovery rate
RNA-seq studies are growing in size and popularity. We provide evidence that the most commonly used methods for differential expression analysis (DEA) may yield too many false positive results in some situations. We present dearseq, a new method for DEA that controls the false discovery rate (FDR) w...
Autores principales: | Gauthier, Marine, Agniel, Denis, Thiébaut, Rodolphe, Hejblum, Boris P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676475/ https://www.ncbi.nlm.nih.gov/pubmed/33575637 http://dx.doi.org/10.1093/nargab/lqaa093 |
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