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FITs: forest of imputation trees for recovering true signals in single-cell open chromatin profiles

The advent of single-cell open-chromatin profiling technology has facilitated the analysis of heterogeneity of activity of regulatory regions at single-cell resolution. However, stochasticity and availability of low amount of relevant DNA, cause high drop-out rate and noise in single-cell open-chrom...

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Detalles Bibliográficos
Autores principales: Sharma, Rachesh, Pandey, Neetesh, Mongia, Aanchal, Mishra, Shreya, Majumdar, Angshul, Kumar, Vibhor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676476/
https://www.ncbi.nlm.nih.gov/pubmed/33575635
http://dx.doi.org/10.1093/nargab/lqaa091